Originally from China, Dr. Wang earned her first academic degree from Wuhan University in Wuhan, China. After completing her Bachelor of Science in Virology, Wang continued on to earn a Master of Science in Biochemistry from the Shanghai 2nd Medical University. Following research activities at both the Shanghai 2nd Medical School and the Chinese Academy of Science, Wang enrolled at the University of Texas at Austin to earn her PhD in Microbiology. Wang then moved on to the Harvard Medical School where she did her post-doctoral work in developmental biology. After serving as an instructor at Harvard’s Medical School, Wang joined the Department of Physical Therapy and Rehabilitation Science at the KU Medical Center in 2005.
Dr. Wang currently works on fatty acid metabolism in energy homeostasis. Her research team is particularly interested in a gene called NADH Cytochrome b5 OxiReductase (Ncb5or). Studying Ncb5or knockout mice that develop lipodystrophy and diabetes, researchers aim to provide new insights into the prevention and treatment of obesity and diabetes.
Specifically, they are studying Ncb5or function in cells, tissues and the whole organism with a focus on fatty acid desaturation, triglyceride synthesis and utilization, glucose metabolism, pancreatic beta-cell function. Using techniques from biochemistry, cell biology, physiology and histology to analyze these processes in various tissues,
Dr. Wang hopes to understand the impact of the overall signaling process on energy balance.
By studying the role of Ncb5or in fat loss and beta cell destruction, the lab aims to more fully understand the early phases of type 1 diabetes. In addition, researches are increasing knowledge about Ncb5or’s biological function in triglyceride synthesis and energy homeostasis, with hopes for new therapeutic drugs to combat type-2 diabetes and obesity.